Trabecular meshwork changes in glaucoma
نویسندگان
چکیده
منابع مشابه
Age-related changes in trabecular meshwork cellularity.
To investigate whether alterations in the cellular component of the trabecular meshwork occur with age, we evaluated trabecular meshwork cellularity and absolute cell number, using specimens obtained from patients ranging in age from newborn to 81 years. We obtained reproducible, quantitative measurements of these parameters, using montages of 1 micrometer meridional sections. A progressive dec...
متن کاملAge-Related Changes in Trabecular Meshwork Imaging
PURPOSE To evaluate the normal aging effects on trabecular meshwork (TM) parameters using Fourier domain anterior segment optical coherence tomography (ASOCT) images. PATIENTS AND METHODS One eye from 45 participants with open angles was imaged. Two independent readers measured TM area, TM length, and area and length of the TM interface shadow from 3 age groups (18-40, 41-60, and 61-80). Meas...
متن کاملMitochondrial damage in the trabecular meshwork of patients with glaucoma.
OBJECTIVES To analyze the frequency of mitochondrial DNA (mtDNA) damage in patients with primary open-angle glaucoma. Oxidative damage plays a major role in glaucoma pathogenesis. Since no environmental risk factor for glaucoma is recognized, we focused our attention on mitochondria, the main endogenous source of reactive oxygen species. METHODS Mitochondrial damage was evaluated analyzing a ...
متن کاملGlycans of the trabecular meshwork in primary open angle glaucoma.
AIMS Glycan expression was compared in glaucomatous trabecular meshwork (TM) and normal TM in order to determine any differences which may reflect pathological changes underlying primary open angle glaucoma (POAG). METHODS Resin embedded TM from trabeculectomy specimens from 15 eyes with POAG and from 12 eyes with normal anterior segments were probed with a panel of biotinylated lectins and a...
متن کاملMorphological variability of the trabecular meshwork in glaucoma patients: implications for non-perforating glaucoma surgery.
BACKGROUND/AIMS Morphological variability of the trabecular meshwork could be of considerable importance for the proper intraoperative outcome of non-perforating antiglaucomatous surgery, such as deep sclerectomy and viscocanalostomy. The aim of this study was therefore to assess qualitative and quantitative characteristics of the trabecular meshwork in glaucoma patients undergoing trabeculecto...
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ژورنال
عنوان ژورنال: Australian and New Zealand Journal of Ophthalmology
سال: 1996
ISSN: 0814-9763,1440-1606
DOI: 10.1111/j.1442-9071.1996.tb00985.x